Simply put Japanese Knotweed is not poisonous, and isn’t harmful to humans like other invasive species. In fact the knotweed can be used as a food source with a taste and texture likened to rhubarb. Apparently it can also be brewed into a type of beer.
Now we are not suggesting you rush out and cook up a nice pie. We have no first-hand knowledge of eating knotweed, and certainly don’t encourage you to try because the off-cuts would need to be very carefully handled. There is plenty of literature online to further any interest you may have in Knotweed as a potential food source. It’s doubtful if this will be the solution for an infested development site though.
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